Use of tianeptine sulfate over-the-counter, literature review, and case report

Introduction Tianeptine is prescribed as an antidepresant in Europe. The prescription drug produced tianeptine sodium. However, it can also be found on the Internet sulfate sold a nootropric. Misuse of sodium has been documented, but there’s little scientific evidence use. Objectives Review use without prescription. Present clinical report Methods PubMed review tienptine Clinical patient using adquiered Internet. Results Systematic search term “tianeptine abuse” conducted 01/10/2022. A total 71 articles were from wich 33 mentioned 23 case reports found. None them made difference between tiaenptine or sulfate. Only one article fora (Smith et al. Am J Drug Alcohol Abuse 2021 47(4), 455–466). years old presented. Diagnoses: ADHD (F98.8); Psychotic episodes four (F23) and two (F16.150) ago; Major depressive disorder (F32.2). Use psychedelics, cannabis, psychoestimulants opioids meeting substance (SUD) criteria. brought proof bought (image 1) for self-treatment his symptoms. prescribed. then restarts opioid with fear new episode oxicodone maintained. interrupts antipsychotic medication suffers psychotic relapse. After this LAI treatment paliperidone started. Currently, recovered maintains psychopathological stability abstinence other substances. Blod test result unaltered. Current treatment: lisdexamphetamine 70mg /day, tianeptina 12.5mg/day; 40mg/12h 150mg /28d. Image: Conclusions believed to present some diferences versus sodium: only through prescrption, daily dose 25mg per day 12.5mg every 8 hours might more potent long lasting. Those differences confirmed by after Self-medication psychoactive substances theories lead disorder. This shows how similar used presription favour therapeutical alliance reduce risk associated non-regulated Further research needed better understand Disclosure Interest Declared